Drug Diffusion Testing
Mott can conduct drug diffusion feasibility studies to help guide the design criteria for your next-generation, controlled-release drug delivery product. Using established surrogate suspensions that serve as a baseline for your unique compounds, our diffusion studies provide a reliable assessment of drug diffusion rates and critical early insight into the form, fit and function of your device. These studies can shorten in vitro test times and reduce scope of in vivo modeling, helping bring your device to market faster.
Controlled Release Testing with Proven Membrane Technology by Mott
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Literature & Data Sheets
Typical Applications
- Low-Flow Drug Delivery
- Implantable Sustained Release
- Catheter-Based Release
- Overdose Protection
Implantable Controlled-Release Drug Delivery Testing
Let Mott conduct your initial drug diffusion feasibility studies to guide the design criteria for your next-generation controlled-release drug delivery technology.
Lab and Engineering Services
Dealing with a complex, critical application? Rely on our engineers and scientists to solve your challenge.
Controlled-Release Drug Diffusion Tech Brief
Mott's controlled-release drug diffusion studies reduce in vitro test time by more than 90%.
Low-Flow Drug Delivery
Mott can customize delivery devices to meet specific requirements to manage extremely low flows for the release of therapeutic agents to optimize patient outcomes.
Product Specs
| Drug Flow Rates |
We can customize passive diffusion membranes in a range of porosities and dimensions to meet drug delivery flow rate requirements and concentration over time. Therapeutic window can be maintained consistently for extended periods. |
|---|---|
| Flow Accuracy |
Achieve consistent zero-order drug release for extended periods at tight dose standard deviation. |
| Device Hardware |
Assemble your flow element into an array of hardware options. |
| Materials |
We employ biocompatible titanium and 316L stainless steel, which have been successfully proven for use in implanted devices. As always, custom alloys and materials are available upon request. |
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Our Design Capabilities
- Customizable, ultra-small components used in implantable devices
- Integrated device concept manufacturing for proof-of-concept trials or transition to production
- Extensive partner network for new materials
Relevant Services
Drug Diffusion Testing: If you need data packages or flow feasibility testing for your molecule or device concept, we’d welcome the opportunity to work with you.
Computational Fluid Dynamics: If you would like to model your process fluids interaction with your Mott-requested part, ask your Mott representative how we can model it using CFD software.
Additive Manufacturing: Controlled porosity 3D printing make it possible to integrate hardware and drug flow elements using a single print.
