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Drug Delivery Implantables

Pharmaceutical and medical device companies are constantly exploring new ways to deliver drug molecules to patients. Through passive diffusion, we can control drug flow rates to achieve a therapeutic dosing window for six months or more using an implantable package. Our solutions are ideal for drugs that require frequent injection or dosage or can cause elevated plasma toxicity levels. They also offer manufacturers new drug delivery options to provide a competitive advantage in the marketplace. Mott can also conduct drug diffusion feasibility studies to help guide the design criteria for your next-generation, controlled-release drug delivery product.

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Controlled Release Testing with Proven Membrane Technology by Mott

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    Literature & Data Sheets

    Typical Applications

    • Low-Flow Drug Delivery
    • Implantable Sustained Release
    • Catheter-Based Release
    • Overdose Protection

    Low-Flow Drug Delivery

    Mott can customize delivery devices to meet specific requirements to manage extremely low flows for the release of therapeutic agents to optimize patient outcomes.

    Implantable Controlled-Release Drug Delivery Testing

    Let Mott conduct your initial drug diffusion feasibility studies to guide the design criteria for your next-generation controlled-release drug delivery technology.

    Lab and Engineering Services

    Dealing with a complex, critical application? Rely on our engineers and scientists to solve your challenge.

    Controlled-Release Drug Diffusion Tech Brief

    Mott's controlled-release drug diffusion studies reduce in vitro test time by more than 90%.

    Product Specs

    Drug Flow Rates

    We can customize passive diffusion membranes in a range of porosities and dimensions to meet drug delivery flow rate requirements and concentration over time.  Therapeutic window can be maintained consistently for extended periods.

    Flow Accuracy

    Achieve consistent zero-order drug release for extended periods at tight dose standard deviation.

    Device Hardware

    Assemble your flow element into an array of hardware options.

    Materials

    We employ biocompatible titanium and 316L stainless steel, which have been successfully proven for use in implanted devices.  As always, custom alloys and materials are available upon request.

    Our Design Capabilities

    • Customizable, ultra-small components used in implantable devices
    • Integrated device concept manufacturing for proof-of-concept trials or transition to production
    • Extensive partner network for new materials

    Relevant Services

    Drug Diffusion Testing:  If you need data packages or flow feasibility testing for your molecule or device concept, we’d welcome the opportunity to work with you.

    Computational Fluid Dynamics:  If you would like to model your process fluids interaction with your Mott-requested part, ask your Mott representative how we can model it using CFD software.

    Additive Manufacturing:  Controlled porosity 3D printing make it possible to integrate hardware and drug flow elements using a single print.